Paraskevi Papadopoulou

Natural Sciences

BSc in Biology, University of California, Los Angeles, Ptychion in Biology, National and Kapodistrian University of Athens; PhD in Biology, National and Kapodistrian University of Athens

Dr. Paraskevi Papadopoulou’s research focuses on the structure and self-assembly of fibrous proteins in biologically significant tissues, such as fish and insect chorion (eggshell), to elucidate protein structure, function, and interactions. She utilizes TEM, SEM, freeze-fracturing, and freeze-etching to visualize fibrillar arrangements at the molecular level. Her expertise includes biophysics methods like laser-Raman, IR spectroscopy, X-ray crystallography, and diffraction to study protein folding and interactions. She conducts biochemical analysis and applies computational and AI tools (AF2&3) for protein sequence analysis and structural prediction. Her research extends to neurodegenerative and genetic diseases, sexually transmitted infections, and cancer. She also explores environmental health, climate change impacts, and sustainability. Additionally, she investigates innovative teaching in STEM and medical education, AI applications in biomedical sciences, digital health (DH) and DH literacy, personalized medicine, and healthcare. As a Senior Collaborator in the Global Burden of Disease Network (GBD), she contributes to global health research.

Selected Publications

  • Velmovitsky P.E., Arbuckle L. and Papadopoulou P. (2026). Editorial: Ethical considerations of large language models: challenges and best practices. Front. Digit. Health 8:1807664. https://doi.org/10.3389/fdgth.2026.1807664
  • Kang, J., Kim, H. J., Kim, M. S., GBD 2023 Substance Use Collaborators (Including Papadopoulou, P.), Shin, J. I., & Yon, D. K. (2026). Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990-2023: a Global Burden of Disease Study. Nature medicine, 10.1038/s41591-025-04137-0. Advance online publication. https://doi.org/10.1038/s41591-025-04137-0
  • Oh, J., Kim, S., Yim, Y., Kim, M. S., GBD 2023 Global Chronic Respiratory Disease and Covid Collaborators (Including Papadopoulou, P.), Hay, S. I., Il Shin, J., & Yon, D. K. (2026).  Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990-2023: a Global Burden of Disease study. Nature medicine, 32(1), 197–223. https://doi.org/10.1038/s41591-025-04077-9
  • Global Burden of Cardiovascular Diseases and Risks 2023 Collaborators (Including Papadopoulou, P.). (2025). Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023. Journal of the American College of Cardiology, S0735-1097(25)07428-5. Advance online publication. https://doi.org/10.1016/j.jacc.2025.08.015
  • Papadopoulou, P.; Polissidis, A.; Kythreoti, G.; Sagnou, M.; Stefanatou, A.; Theoharides, T.C. Anti-Inflammatory and Neuroprotective Polyphenols Derived from the European Olive Tree, Olea europaea L., in Long COVID and Other Conditions Involving Cognitive Impairment. Int. J. Mol. Sci. 2024, 25, 11040. https://doi.org/10.3390/ijms252011040
  • Papadopoulou, P., & Lytras, M. D. (2025). Enhancing patient welfare through responsible and AI-driven healthcare innovation: Progress made in OECD countries and the case of Greece. In Next Generation eHealth (pp. 33–77). Elsevier. https://doi.org/10.1016/B978-0-443-13619-1.00003-9
  • Papadopoulou, P. & Lytras, M. (2023). Advancing precision medicine in medical education: Integrated, precise and data-driven smart solutions. Appl. Res. e202200131. https://doi.org/10.1002/appl.202200131
  • Papadopoulou, P., Galanopoulos, V. K. & Hamodrakas, S. J. (1996) Molecular and supramolecular architecture of the Salmo gairdneri proteinaceous eggshell during development, J. Struct. Biology, 116:399-412